Current percutaneous recanalization of coronary chronic total occlusion.

Although successful recanalization rates of coronary chronic total occlusions have remained suboptimal in percutaneous coronary interventions, evolving techniques, including the retrograde approach, have raised hopes for better outcomes. With the advent of antiplatelet therapy and drug-eluting stents, along with conventional antegrade approaches, further progress can be expected in the "last frontier" of interventional cardiology. The article focuses on contemporary recanalization strategy in percutaneous coronary intervention of coronary chronic total occlusions.